hrp0082p1-d1-184 | Perinatal and Neonatal Endocrinology | ESPE2014

Very Low Birth Weight <1500 g is Associated with Reduced Sex-Typical Behaviour in Childhood

Sankilampi Ulla , Hines Melissa , Lamminmaki Annamarja

Objective: Low birth weight and prematurity are linked to various behavioural outcomes. In addition, preterm (PT) infants show altered maturation of pituitary–gonadal axis, as demonstrated by its pronounced transient activation during the first postnatal months. Given that gonadal steroid hormones shape the basic processes of neural and behavioural sexual differentiation these elevated sex steroids in premature infants might affect the developing brain and alter subsequen...